Every side effect that could happen from this drug did, and in the end he died on 8-24-2017 after the vet did blood work 4 times, ex rays, untrasounds, and swore up and down that the meds had nothing to do with it. I read all the side effects from the study and didn’t know what to do. References. It was told to us in private that the long term effects of the Apoquel could be the cause of her cancer. 1 Tuddenham WJ.Glossary of terms for thoracic radiology: recommendations of the Nomenclature Committee of the Fleischner Society. I do not believe there was enough testing done on this drug. Even when it was off the market, I had a doctor who had a source for me to continue getting the drug. My 4yo Yorkie has been on Apoquel for 5 months. No more for my precious girl! This saved his life. The routine veterinarian drug did not bring it down. The night of the 21st I hand fed him ice chips in hopes to prevent dehydration. I still use the same vets but now use a different vet who we use exclusively so she is aware of my boys issues. After 3 days she is back to scratching, licking and bighting again with enflamed skin and a lot less energy. I have three Shih Tzu on Apoquel for three months. Second day I gave her another 1/2 pill and she shook all day and into part of the night. He was finished. I think I will try the lady Ann’s recipe and see if that helps her. The vet could not detect what was wrong with her so this means a whole lot of blood test. When we took her out to potty, she was randomly falling down and her back legs were very unstable. Please read and research this drug before giving it to your dogs. Gets up on the Saturday and couldn’t find him. Can any of these symptoms be reversed or are they permanent damage? Last year we tried Apoquel. One morning I got up and he was shaking in his cage and couldn’t lift his head. Her creatinine went from 8.0 to 0.3 – almost normal!! She is supposed to go from 2 to 1 a day in 3 days. (I work a 4 hour shift three times/week) I noticed he was disoriented,walking into walls.He was well enough to go for a short walk. Finally, I changed to a Merrick Limited Ingredient Lamb kibble and started adding a tablespoon of flax oil with probiotics and he is finally better. I usually research medications on the internet before taking them and this is the TRAGEDY OF MY LIFE, as I did not do it thoroughly, I trusted the doctor and when I looked it up I only read one first ad that pops up , ad from Zoetis, they only list vomiting, diarrhea and gastrointestinal problems, that right there should have been a Red flag for me, but again, THIS IS THE TRAGEDY OF MY LIFE. So I stopped Apoquel after 3 weeks and she was better the next day. Plus wipe those feet after being out. I hope we stopped this drug in time before more serious damage happens. seizure. I don’t think so.. don’t use this drug! She was only on med for 2 weeks, had a stroke and stopped breathing on the way to try and get her help. I should have ask questions… I usually do. I took him off Apoquel for a week and his symptoms totally disappeared; however, I put him back on Apoquel because the vet was convinced the drug was not responsible for his lameness. Good.”… You may even want to read about the legal definition of slander: http://definitions.uslegal.com/s/slander/. She can’t see or smell food an inch from her nose! The potential for serious side effects is substantial, and that 1/3 of dogs did not respond in the study. The vets are making a fortune off this drug and the injections that is why they are pushing them. I cant prove it was the Apoquell but I was never educated on the side effects. She was going through heart and liver failure. Normal levels are between 0-200 – my dogs were 2,000. I have read your comments about your pets having side effects. Let these people talk about what they think about this drug. The doctor along with us are monitoring all. I love my dog way too much to simply take the risk. He had been off and on apoquel for the last 3 years with recently consistently for the past 3 months. My jack russel x has been on apoquel for only a few weeks but has quickly developed what looks like a fast growing tumour under his shoulder, do you think this could be related? It was not the first thing we tried. My 10 year old Rat Terrier was prescribed Apoquel 3.6 for 30 days on Oct 6, 2017 due to her itching. AJR Am J Roentgenol 1984; 143: 509–517. Makes me nervous.. At first I was like, ‘I’m worried now” But its a bit of a scare tactic. Is there another page that I’m missing. Then he began acting weird one day starting with having diarrhea then he started panting, drooling, pacing, sitting on my chest I knew something was wrong and went to the animal emergency room. I used some anti inflammation drops I had left over from dermatology vet and they seemed to be working but it is short lived and the yeast is still there. He has received a daily dose consistently for the last 30 days. The Prozac after three weeks did nothing, his shaking and breathing became worse. 2 days off—noticeable improvement. She was still eating and seemed a little more tired so I wasn’t alarmed. I believe some of the vets push it because it is expensive. 10 is way to young for my dog to die. THIS DRUG KILLED MY DOG. I cooked for him for 8 years because he wouldn’t eat dog food. I was considering Apoquel for my 8 year old German Shepherd. My 4 year old Yorkie was put on apoquel. Fuck this drug. I certainly want her to be happy but also healthy. He is still itchy but will go back to Benadryl and an oatmeal bath weekly. our 17 year old cairn terrier has been on Apoquel for 4 mos. Thanks again Dr. Jones. Multiple doses of antibiotics for skin infections. Go ahead with apoquel. When we arrived, Ginny pooped alot which I thought was because of the travel. Then came the seizure. He’s been to Cornell, and we have tried just about everything. After this it was too late for her they said she had I WOULD NOT recommend giving Apoquel to your pet!! When we told the vet we wanted to discontinue this because of the side effects she acted like she has never heard of anyone having hear issues before. I think a class action suit against the makers of apparel is called for. I then halted the Prozac completely and my friend is back. Drugs.com is where I found all the horrible side effects of the drug and it was too late. If not I’m going back to the vets. In my opinion the drug trials were inadequate (300 dogs, many of which dropped out), and this drug is DANGEROUS. We even had a needle biopsy done. I continued with the Apoquel thinking that if I’m patient, things would get better with time. She recently started peeing her bed and on the floor. Our dog, Casey, 15.5 years old ,bishon, has severe allergy problems. acute, short-term condition or can be recurrent or chronic—all which can impact the and said everything is normal, probably will never happen again. APOQUEL (oclacitinib) manufactured by Zoetis, I talked with a Homeopathic vet about my dog and this med and she said that she is seeing at least 4 dogs a week that are coming to her because of reactions to APOQUEL. It really seemed to help with the hacking and coughing and all. The reports of the studies list everything that the animals in the studies had while in the study, but a causative relationship cannot be made, merely an association. Here is my dilemma. My 10 year old Maltese 10 pound has had intermittent allergy problems his entire life. As another poster mentioned she was panting, in pain and suffering. Just as I was dozing off, she abruptly sat up and started crying. 2 days ago, on daily dosing st this point, he had another. Fourth Quarter 2014 Reported Net Income of $126 Million, or $0.25 per Diluted Share, Increased 20% and 19%, respectively He chews at his hind quarter, scratches at his paws and ears keeping me up at night. I agree. So in the midst of all of this… I did notice that her pet food had changed gradually and I finally took the last case back and put her on another food… just in case it was a food additive issue! No more Apoquel for my dog! with all I am reading, I am not sure if I will continue her on it or not. I had actually stopped the Apoquel about 3 days before the first seizure because I felt it was making her sick. Finally the neurologist did and MRI and found no stroke, no tumor, her blood vessels looked good and she was over 6 yrs old. IF your dog has allergies, he needs to be on these. Health events associated with the drug were difficult to compare between groups given the low number of dogs in the placebo group at the end of the study. She was starting to feel a little better we thought but then she died the day after Christmas 2016. You can check http://www.orthomolecular.org for more research and info. We thought we were going to lose her. Still itching and the straw that broke the camels back was seizures. She is on Revolution and I have never seen a flea on her. This is not like him.So I am going to quit giving him this med. We did try a restricted diet and the diet didn’t affect his scratching. When we found the new vet he said he wanted to try Peatie on a new anti-itch drug…pricey but effective. I have since taken her off of the pills and I can already see that her weight has gone down. Seonaid, what dose are you giving your westie? so I went back to my regular vet I trusted who pit Ollie on ever increasing steroids to try to kill this yeast infection. She was my baby and dearest friend. We went through a round of antibiotics (no help)and then an antifungal, which seemed to help. But it continued, the swelling, around the legs, his body was swollen, around his eyes. I looked up side effects and was horrified. My vet diagnosed him with 3 different bacterial infections which I’m assuming he got from his immune system being compromised from this drug. It would be easier or me to inject her with something than get her to eat EFAs, probiotics, or administer colostrom. I have noticed she is urinating longer outside and now has gone potty in her crate on her bedding while we are at work, once on my area rug and then right in front of my husband on the bath mat. I supplement benedry to keep the itching controllable at night. She had gained 17lbs since July. I certainly don’t want to cause the side effects that I read. Apoquel is an amazing Medication, I have a boston terrier and he has allergies to oak pollen and other blooming plants in the spring, he has been on apoquel severeal times throughout the past 2 years, for this condition, yes i have tried benydryl and he eats dog food with fish in it, by far apoqeul is the best medication to treat his allergies, no more itching, clear shiny coat again and is back to regular playful self, I give him 3.6 once a day and that does it, no side effects for Him. This drug should be taken off the market! So we are finished with it for good. I was prescribed Apoquel for my 9 yr old pug with hot spots when I told my vet that I was concerned about the possible long-term effects of using Benedryl regularly. Now, just do the rest of the world a favor and drop off the face of it and stop trying to scare people into doing what you want and believing what you think is correct. Within the first 12 hours he developed runny poop and lethargy. It has been launched with much fanfare…from Zoetis.. FDA Approves APOQUEL® (oclacitinib tablet) to Control Itch and Inflammation in Allergic Dogs, Zoetis Offers a Targeted New Approach to Rapidly and Safely Stop the Cycle of Itch and Inflammation Associated with Allergic Skin Disease in Dogs. Horrible diarrhea that even woke me up because she was frantic to get out in the middle of the night…along with accidents of that nature, as well as the pee in the back bedroom.. (thank goodness we have hardwood floors). My dog has very bad allergies. I cut the dose by half and this side effect stopped. BTW, these meds did not come with the normal info sheet, just directions on the bottle. My 11 year old peekapoo has been on Apaquel for two weeks.she doesn’t have any itching but now she is having resulting issues and has trouble breathing. I am so grateful to have finally found something that works and is healthy for her. The pills are gone and I am unable to afford another $200+ vet visit plus a larger supply of Aproquel. Our dog scratches till she has raw sores on her stomach underarms and other I’m heartbroken that I didn’t do my due diligence on this medication. Early Tuesday Nov 21 my husband woke me up to tell me that Ginny had let put a help and was very weak and could not stand up on her own. Hold dig opdateret. (causing cancer (B-cell lymphoma) seizures (get a blood count He was diagnosed with severe pancreatitis. RBC 26,000, PLATELETS 50,000!!!! They started having trouble. He has always had a scratching, itching biting skin problem. I knew saying good bye would be difficult, but I … My vet says its allergies causing it. After just a few days the panting and pacing was constant, she never stopped and didn’t sleep. http://www.fda.gov/AnimalVeterinary/SafetyHealth/ProductSafetyInformation/ucm055369.htm. Apoquel wont work for my pin , her itching decreased, but never stopped, and it has side effects. He is a cocker spaniel who is now just over 10 years old. Vet was not aware of all these side affects because I had asked right after starting her. Liver counts are high is some areas so we will check again in two months. A little research showed that the Rx was twice the recommended amount for her. Last week we had to say goodbye. I’m going to discontinue and if the itching returns, begin with 1/2 the recommended dose. I’ve tried everything to ease her itching, and she’s been on hydroxyzine for a few years with limited success. The day I bought the second months prescription at the cost of $105 my dog began having bloody diareah. … was up all night with the poor little guy, he was panicking badly, jumping into my lap, whimpering, panting,he was doing a weird head stretch thing ,could not settle, drinking loads… stopped the apoquel,took him to emergency vet, had bloods etc checked & they said he was fine…. I decided to look up the side effects of Apoquel, as that was the only thing that was new and I wondered if GI upset and diarrhea could become an issue while on it. He has also been drinking excessively since we started him on the drug and peeing in the house as well. Bald from chewing, scratching bleeding, pus coming out of his eyes and chronic ear infections, bad yeast odor. There is a NEW drug on the market to control itching in dogs from allergies, called Apoquel. Ruined 6 months of our lives. It was a blistery, painful looking infection. bill will be higher too. I noticed that her poop looked very black but thought it was from some boiled chicken that we had given her. diarrhea, vomiting, and lethargy that resolved spontaneously in 90% of cases and did not His spleen burst And blood was leaking into his abdomen they took blood and x-rays and found out that he had also cancer in his lungs, from the medication I would never put any dog on this medication ever and called the company and they still still will not say that the medication causes that issue even though he was healthy happy and the best dog and we had to put him to sleep at 4 1/2 years old due to him taking Apoquel. Negative for parasites or Parvo. The first 30 days there seemed to be no side effects, his appetite was good and it stopped the itching immediately upon the first dose he received. I ended up at the emergency hospital where he was put on antibiotics, IV’s and had X-rays, bloods and ultrasounds done. management. He is now on phenobarbital for life because the seizures never went away. I stopped all grains just fed human meat and veggies, sweet potato with vitamins daily added to food like Genestra brand Acidophilus HMF intensive powder, most important 15 mg Zinc, small amount of dulce flakes for iodine, Hilary’s vitamin mineral powder or similar from a pet store, 1 enzyme with bromelain and papain and Quercetin (or Genestra Super Flavonoids 1 capsule) all 3 work together. I ran to the vet and asked for more…$55 later, I had another months supply. I hate that we now must take him off the medicine because he has been able to live a more comfortable life, but I can’t ignore the side effects and how it’s affecting him. He had to have the dosage raised today after 2 seizures this morning. We had tried everything, including allergy shots. I took him to my vet who then sent me to Emergency. He is the sweetest pup and has been through so much and I am so frightened that we could lose him next time. Nothing worked. The vet put him on Apoquel 16mg a day. She runs into everything and everyone. He has symptoms of Cushings from longterm use of the Pred and he has a heart murmur. When he didn’t come back, I went to check, he had diarrhea in 2 different places. So I would take care to note if you see her drinking more than usual. My little girl now has ringworm, extremely high levels of protein and blood in her urine, low albumin. I have a 90 pound mixed male Shar pei who has been on Apoquel 3 years now. He is still on hepaticlear..3 years later. I’m convinced this drug killed my baby girl. It was prescribed by his dermatologist. We are going in this evening to put him to sleep. I only hope my baby “Stoney” will be Ok. We would like to show you a description here but the site won’t allow us. Wow!!! …..for a few weeks. A small study of 299 dogs- 50% of the dogs took the placebo medication, and most dropped out of the study. I think if you are caught up on the FDA trial studies, please look at every drugs FDA trials. However, he also developed skin growths right around that time and they will not go away. When we took him in, the nurse noticed bumps on his back and the vet (a new one) decides that it is a skin infection and prescribes(without permission) Cefpodoxime and Apoquel. He has been on this drug for three years and his allergies are gone. She set up an appt. I am convinced that apoquel is the cause and I would like to know if his liver enzymes will return to normal now that apoquel has been stopped. Share photos and videos, send messages and get updates. He has urinated in front of me, also not wanting to stay outside, or even go outside. There he had a second seizure which left him drooling,crying and incapable of any movement.I had no choice,I chose to relieve his pain. It did work. Her ALT is-349, ALP-567 and billi is normal 0.1. It has been 32 days now and felt it was almost time for her to go, she stopped eating for three days but was still drinking some water. No more. We ended up going to another vet and doing more tests and she was diagnosed with a cancerous tumor in her chest cavity, this was around late October 2016. As I write this I just want everyone to know….the drug may stop the itching as it did with my dog, but it allows the immune system to weaken and your dog won’t be able to fight off the most basic thing: fungus. Being very worried, I began doing research on the Apoquel the vet had given her and was shocked to find out its an immunosuppressant with some ugly side effects. Sandra. He takes 16 mg. daily and the scratching has almost stopped. Hamish is very threadbare and I have been loathed to clip him. nothing major yet -except she doesnt DO NOT GIVE APOQUEL TO YOUR PET. Kudos to the very few who this drug has helped, I will not be taking that gamble. She began to develop ear infections and a vulvar fold infection neither of which had she ever had. I contacted the makers of this pill. At the beginning of Spring of this year. We can leave for work and they are both fine. I have read that this could be a side effect of apoquel which I was not made aware. If you’re wondering how I treat my dog’s allergies, I focus on diet. I have a 3year old german shepherd, itching like crazy Apoquel helps it keeps the itching undercontrol however he want to be outside all the time to pee, which is fine. Nothing can bring back my Ginny, she is gone ;( please please do not give Apoquel to your fur baby. Has been on short term antibiotics and steroids for secondary skin infections. For the prescriptions !!! I have read some of the negative comments here and all I can say is… This new vet prescribed Aproquel 16mg (twice daily 14 day supply) for a chronic allergy problem, we think from the cat. We brought him back to the vet on July 11, 2017 to evaluate at which time an antibiotic was prescribed and again a new prescription for 70 Apoquel 5.4mg tablets at a cost of $126.00 for the Apoquel. Please listen to Dr. Jones. He will not walk again–they think the infection is in his spine now. Luckily the infection resolved without injury to her eyelid or sight. She gave my dog Prince Si Miao Four Marvels Formula (can buy this online) I gave a 1/4 or less amount that a human would take for 4 months (herbs must be watched not to take for long periods of time so look for any side effects like blood in stool) . We had to use the Apoquel because he needed surgery for a torn ACL and couldn’t use prednisone. Very unlike him and the bowl belongs to a dog that visits a lot and he is head over heels in love with. I am having the same issue as Kelly noted above. The next morning at 5AM the same thing happened. We did zyrtec lorantidine vistari We went back inside and for the rest of the night she cried and stared off into space. Too few veterinarians are explaining the risks. Your article leads people like Lynn with the yorkie to jump to blaming Apoquel for her dog’s health issues with nothing to substantiate her claim. I chose to start frequent washing with 3% BPO shampoo to deal with the yeast infections from allergies, (at least thats what the vet told me was causing this). So, on Apoquel she went. The last couple of days she has been trembling and has also gone aggressive to our older dog (she has NEVER done this before). I had her for 11 years. Well after about 4 mths I couldn’t take it anymore. He is so sick he can’t pick his head up. He has a low platelet count. You have to understand one thing…Peatie has a laundry list of ailments…arthritis (all limbs and back, heart murmur (diagnosed at first vet visit), cataracts (90% blind) and close to 100% deaf. It’s only been one week so I don’t expect a miracle. I guess I need to do some more research. On nights 22, 23,25 she had huge seizures, the first waking me with loud howling and all ending with her peeing. I was NOT told it suppresses the immune system, but it absolutely does. I have two westies on apoquel, both have problem skin. Also she was not falling down for no reason. I am taking my dogs off of this. We stopped giving him the poison on the fifth day. He has been on Prednisone since he was 10. He cried and was unable to walk correctly. mini stroke. Best regards Was it worth it? If Zoetis produces the vaccines that were used…well that would truly answer a lot of questions. neutrophil, eosinophil, and monocyte counts decreased among dogs in the oclacitinib group I went to the FDA website and there is not one complaint that I can find from any vet or pet owner. I was at my wits end after failing to relieve his itch, but I refuse to subject my love to seizures and liver damage. But I will never use these medications again and will find alternative methods of controlling the infections, i.e. DO NOT GIVE THIS POISON TO YOUR PET. I have to give her water from a bottle or syringe. It’s nice to see her not so stressed out over scratching and with a beauriful full coat. He kept breaking out in scabby smelly yeasty sores which would eventually turn the skin black and constantly itching and scratching. There should be some mornings to the vets, but there aren’t. Bit worried my E.R. She was given apparel which seemed to work well. I was aware of the risks involved with this drug and was well informed both by my vet and also by my own research before beginning his treatment. I think it could be a very dangerous drug. After reading the comments here I will not be continuing on Apoquel. She has kept me awake for the last few nights constantly getting up and wandering because she feels so sick. Having treated hundreds of dogs for allergies, it is MORE than welcoming to have a drug that works to STOP the itching without all the side effects of predisone. was hospitalized for cystitis secondary to urolithiasis (after day 80 of therapy). NO. And Grandpuppy has a history of urinary tract issues, but after starting Apoquel her urinary tract problems are blamed on it by her owner. Apoquel scares me with with how quickly my frenchie started getting infections, instability, diarrhea and was still mildly itchy (probably from the yeast infections she was getting). She began taking it in Nov. Of 2019. For slight allergies try otc antihistamines like Zyrtec. I hope you don’t still practice medicine. God knows how he pulled through but after 5 days he was on a turn in the right direction. Bit worried about that. 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